Predictive Genetic Test

In 1993, scientists discovered the location and function of the gene that causes Huntington’s disease (HD). Since then individuals who are at-risk with no symptoms of HD can undergo genetic testing to learn if they have inherited an expanded copy of the gene and will, therefore, develop the condition in the future. This is called ‘predictive testing.’

It is important to note that pre-symptomatic testing for HD cannot determine when the disease will begin or its course or severity. People who test positive for the gene may remain healthy for many years. HD can only be diagnosed by a neurological exam.

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For a long time, little was known or published about HD. In the last 30 years, however, we have learnt a lot about the cause of HD and its effects, as well as the therapies and techniques for managing its symptoms. The gene that causes HD was discovered in 1993 and since then important scientific advances have been made.  To date, there are no drugs to slow or stop the progression of Huntington’s Disease, but scientists are getting closer each day to finding a disease modifying treatment.

HD causes gradual degeneration of brain cells which in turn can result in physical, cognitive and emotional symptoms, which typically become apparent between the ages of 35 and 55, but can also appear much earlier (Juvenile-Onset HD) or later (late onset HD).   

In most cases, individuals affected by HD can maintain their independence for several years after the first symptoms appear. A knowledgeable physician can prescribe treatment to minimize the impact. Allied health professionals, such as social workers, occupational and physical therapists, speech therapists and nutritionists, can all play a useful role in maximizing abilities and prolonging independence.